Sagan's achievements on the bike are matched by his colourful personality off it.
Six green points jerseys for most consistent finisher at the Tour de France attest to his all-round abilities. He has also won the world road road title for the past three years and took the inaugural elite men's European crown in 2016.
Sagan will relish the challenge of the 230km looped city-centre course, where the riders' victory prayers will be answered - or not - on the 16 climbs of St Vincent Street and Great George Street before the finish at Glasgow Green.
Sadly, the expected clash between the Slovakian and Britain's Mark Cavendish will not take place after the 2011 world road race champion withdrew on medical advice after a year blighted by injury and illness.
Cavendish was relishing a sprint battle over the course where he won the national title in 2013.
Post Tour de France victory celebrations and scheduling mean Geraint Thomas (GBR) will also be unable to add to the Commonwealth Games title he won in Glasgow after an epic attack in a rain-lashed race in 2014.
But there are plenty of other top-class riders ready to thwart Sagan's attempt to add another winner's jersey to his huge collection.
Among them is Norway's defending champion Alexander Kristoff, fresh from winning the final sprint on the Champs-Elysees at the Tour de France last month.
Germany's John Degenkolb and Belgium's Greg Van Avermaet have also proved they have the ability to tackle the punchy climbs and still have the energy for a blistering finish.
Other names to look out for are Britain's Scott Thwaites, who took Commonwealth Games bronze in 2014, and Sonny Colbrelli, who will be looking to spring a sprint surprise and make it an Italian double after Marta Bastianelli's victory in the women's race on 5 August.